UCLA is 9-0 straight up and 5-3-1 against the spread in its last nine meetings with members of non-Power Five conferences. Memphis, meanwhile, is 3-5 SU and 5-2-1 ATS over its last eight meetings with members of the Power Five. The Bruins make a rare venture east of the Mississippi to take on the upset-minded Tigers on Saturday afternoon at the Liberty Bowl.
College football point spread: The Bruins opened as 6.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 21.