Oklahoma dominates the all-time rivalry with Kansas State, leading by a 74-19 margin with three straight wins. But the Wildcats have actually taken two of the last six meetings straight up, and they're 4-4 against the spread over the last eight, keeping several games close as underdogs. Kansas State is a big underdog for Saturday afternoon's clash with the Sooners in Norman.
College football point spread: The Sooners opened as 21.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 48.