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College football's five biggest Week 5 questions include Oklahoma State, Alabama

Related Topics: Alabama

Heading into the biggest weekend of the college football season so far, there's a multitude of matchups that will pique people's interest across the country.

The ACC and SEC each have two showdowns involving ranked opponents with one each involving teams among the top 11 in the USA TODAY Sports AFCA Coaches Poll. There's also a key clash in the Big 12 featuring the two teams that made the conference championship game.

Each of these showdowns could come down to one key matchup that determines the winner and loser. To address those potential turning points, here are the five biggest questions for Saturday:

Who wins the quarterback matchup between Spencer Sanders, Blake Shapen?