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College Football Picks: Week 6 Predictions for Every Game

Conference play brings out the best (and worst) in teams, as we saw last week, as many of the biggest upsets involved teams from the same league. And with the vast majority of games on this week's college football schedule of the intra-conference variety, expect more surprising results.

Though maybe not as many, since the Week 6 slate isn't nearly as thrilling as what we witnessed a week ago.

There are only two matchups of Top 25 teams on Saturday, one in the Big Ten and another wrapping up the night out in the Pac-12. League play does dominate the weekend, as 49 of the 57 games are conference clashes, including the first Tuesday night game of the year on Oct.