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College Football Picks Week 1: Predictions and Odds for Top 25 Schedule

Week 1 in college football begins a four-month odyssey expected to take several twists and turns while the College Football Playoff debate rages on.

The first full weekend slate of the 2018 regular season features four showdowns between ranked teams, with the top-10 clash in Atlanta between Washington and Auburn acting as the headliner.

The renewal of the Michigan-Notre Dame rivalry receives top billing Saturday night, while Miami and LSU square off Sunday and a pair of ACC titans clash Monday.

Below is a look at the latest odds for Week 1 and predictions for each contest involving a top 25 program.