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College Football Odds Week 3: Picks Against the Spread and Score Predictions

The ACC commands the college football spotlight in Week 3.

Saturday's primary game pits the Miami Hurricanes against the Louisville Cardinals in a matchup of teams looking to establish themselves in the second tier of the ACC beneath Clemson and Notre Dame. That clash will be a nice showcase for both teams and the conference, which will likely take a back seat to the SEC when it returns next weekend.

The Georgia Tech Yellow Jackets were expected to finish near the bottom of the ACC, but they surprised everyone with a road win over Florida State in Week 2.