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College Football Betting Odds Week 1: Picks Against the Spread for Top 25 Schedule

Two of the most fascinating games involving Top 25 college football teams take place on Sunday and Monday of Week 1.

The neutral-site clash between the LSU Tigers and Florida State Seminoles in Orlando is the marquee matchup of the slate.

Both LSU and Florida State come into the 2023 season with a ton of expectations, as evidenced by their respective top 10 rankings.

LSU is expected to take a step up in Brian Kelly's second year in charge, while Florida State could cash in on returning a ton of starters from 2022, including quarterback Jordan Travis.