In theory, any college football player can win the Heisman Trophy. Reality, however, has told an incompatible story.
Since the Heisman was first awarded in 1935, a quarterback or running back has hoisted the prestigious honor in 79 of 86 seasons. Lately, it's been a QB-dominated award; 17 of the 21 winners in this millennium played the position.
Alabama wide receiver DeVonta Smith interrupted the trend in 2020, but voting tendencies are well-established and very likely to continue.
There is good reason for this QB-centric inclination. Quarterback is arguably the most important position in all of sports, let alone football.