Henderson made the announcement on Twitter. The middleweights will headline the upcoming UFC Fight Night card in Sao Paulo, Brazil, on Nov. 7.
Geez, I didn't realize how impatient mma fans are for their news. I'm fighting Vitor on Nov 7th in Sao Paulo.
— Dan Henderson (@danhendo) August 2, 2015
Belfort and Henderson fought for the first time in 2006, when the American came out victorious via decision, but the Brazilian got his revenge in 2013, scoring a first-round knockout in Brazil.
"The Phenom" enters the bout coming off a first-round loss to middleweight champion Chris Weidman, while "Hendo" looks for his second straight victory following a devastating win over Tim Boetsch.