Detroit Tigers star Miguel Cabrera was placed on the 10-day injured list due to a left biceps strain, via ESPN.com.
The first baseman was replaced in the ninth inning of Saturday's loss to Cleveland.
Former Baltimore Orioles first baseman Renato Nunez was brought up to replace him. The 27-year-old hit 43 home runs over the past two years and signed with Detroit on a minor league deal this offseason.
Cabrera, who turns 38 on April 18, spent the offseason training for a return to first base after spending the shortened 2020 campaign as the Tigers' designated hitter.