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Houston Astros vs. Boston Red Sox ALCS Game 1 Odds, Analysis, MLB Betting Pick

The defending World Series champion Houston Astros will try to continue their recent success at Fenway Park on Saturday when they visit the Boston Red Sox as small road underdogs at sportsbooks for Game 1 of the American League Championship Series.

The Astros have won six of the last nine games played against the Red Sox at Fenway, according to the OddsShark MLB Database, and knocked them out of last year's playoffs with a 5-4 victory in Game 4 there. Boston will be out to avenge that defeat.

MLB betting line: The Red Sox opened as -110 favorites (wager $110 to win $100); the total is at seven runs, according to sportsbooks monitored by OddsShark.