First there was the slide, and then there was the career slide for Dustin Pedroia.
In April 2017, in a game between the Boston Red Sox and Baltimore Orioles, then-Orioles third baseman Manny Machado made an aggressive and arguably dirty slide into Pedroia at second base. He hit Pedroia's calf and indirectly injured his left knee:
You can argue the aggressive vs. dirty distinction. To his credit, Machado immediately put his hands on Pedroia with seeming concern.
Later, Machado told reporters the takeout nature of the slide "wasn't intentional.