The Angels pulled away in the fifth, an inning that saw them bat around and plate five runs. With the bases loaded and one out, C.J. Cron hit an RBI single, Jefry Marte worked a walk and, with two outs, Jett Bandy hit a routine fly ball that Twins right fielder Max Kepler lost sight of, scoring two more runs. The next batter, Andrelton Simmons, rolled an RBI single through the right side, giving the Angels a 7-1 win to eventually take two of three in the series.
Santiago entered with a 12.