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Santana hits 1st HR of '18 as Crew drops opener

MILWAUKEE -- Domingo Santana cleared the fences for the first time in his 100th at-bat of the season, but the Brewers were unable to shake their troubles against winning teams.

Santana's two-run home run capped a three-run sixth inning rally for the Brewers, who played from behind after the Pirates hit a pair of two-run home runs against Junior Guerra in Milwaukee's 6-4 loss on Friday at Miller Park.

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The Brewers fell to 5-13 against teams .500 or better on the year. They are 14-1 against teams with losing records.