After winning the opener in their home series against the Padres, the Brewers struggled in game two. Corbin Burnes was on the mound for the Crew against up-and-coming star Joe Musgrove. Burnes had picked up right where he left off last season, as a reigning Cy Young winner. Musgrove has pitched well since the beginning of last season and pitched a one-hitter against Milwaukee on Friday.
San Diego jumped on the board early, when Voit hit a ground-rule double that scored Machado. The Padres led 1-0 after one inning. They would score again in the top of the second off Burnes, when Jurickson Profar hit an RBI single that scored Grisham, putting the Brewers down two runs.