Middlesbrough will assess George Friend, who is back in training after a knee problem, and fellow defender Calum Chambers, who has a shoulder injury.
Boro will also monitor Gaston Ramirez and Cristhian Stuani, who are both nursing foot problems.
Swansea may again be without Ki Sung-yueng and Federico Fernandez, both of whom are recovering from a broken toe.
The likes of Mo Barrow, Borja Baston and Jack Cork may earn recalls if boss Bob Bradley opts to rotate his squad.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: "Earlier in the season, Aitor Karanka spoke about "our league", by which he meant the importance of games against the other teams set to battle it out near the bottom.