Arsenal midfielder Granit Xhaka begins a three-match suspension on Saturday as a result of his red card last week.
Santi Cazorla is a fitness doubt after taking a kick to his Achilles against Ludogorets on Wednesday.
Middlesbrough head coach Aitor Karanka has no fresh injury concerns.
Club captain Grant Leadbitter is back in training after undergoing hernia surgery during the summer, but Saturday's trip is likely to come too soon for him.
MOTD COMMENTATOR'S NOTES
Jonathan Pearce: "Seven wins in a row have Arsenal as the best team in England right now.