Midfielder Marten de Roon will not figure in Middlesbrough's Sky Bet Championship clash with Sheffield United after he sealed a move back to former club Atalanta.
The Italians were given permission to speak to the 26-year-old after the clubs agreed a fee for the man who cost Boro B£12million last summer.
Adam Forshaw could get the nod to replace De Roon, while striker Patrick Bamford staked his claim with an impressive display as a substitute after replacing summer signing Ashley Fletcher in last Saturday's 1-0 defeat at Wolves.
Fletcher was one of six debutants for the Teessiders at Molineux along with Darren Randolph, Cyrus Christie, Jonny Howson, Martin Braithwaite and Britt Assombalonga.