On Monday night in Orchard Park, N.Y., he connected on 29-of-45 passes for 324 yards and two touchdowns in a 25-6 victory.
The AFC East rivalry is so lopsided that Brady has more wins in Buffalo than any Bills quarterback since 2001.
At 2,200 passing yards for the year through eight games, he is well on pace to cross the 4,000-yard barrier for the ninth time in his 19-year career.
He managed to poke fun at himself on Instagram for nearing another “accomplishment,” as he carried the ball once for eight yards.
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He stands at 997 career rushing yards.