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In November 2024, the Michigan Wolverines pulled off a memorable upset vs. the Ohio State Buckeyes, beating their longtime rival 13-10.
Check out the 10 biggest college football point-spread upsets over the past 30 years.
1. Howard Bison (+45.5) over UNLV Rebels
Sept. 2, 2017
It's only fitting that the biggest upset in college football history would happen in Las Vegas. For a team to win as 45.