Just days before their high-profile rivalry game, No. 2 Ohio State is a 7.5-point favorite over No. 3 Michigan.
Throughout the season, sportsbooks offer an advanced line on marquee games that generate wide betting interest. Each week, based on recent performances and other developments like injuries, oddsmakers adjust the odds.
"On a neutral field, we have this game around Ohio State as a 4.5-point favorite so we're giving the Buckeyes roughly an additional three-point advantage for playing this game in Columbus," Caesars Sportsbook lead college football trader Joey Feazel told ESPN. "The spread will depend heavily on (Blake) Corum's status throughout the week.