Despite a frantic fourth quarter comeback attempt from Notre Dame, Michigan State held on for a 36-28 win over the Irish in South Bend.
Michigan State's defense allowed 21 straight points after going ahead 36-7 in the third quarter.
Tyler O'Connor finished 19-of-26 for 241 yards, two touchdowns and an interception for the Spartans (2-0).
Donnie Corley (Detroit King) had four catches for 88 yards, including his first collegiate touchdown in the second quarter. R.J. Shelton caught eight passes for 80 yards and a touchdown.
Gerald Holmes had 13 carries for 100 yards and two touchdowns, while L.