Odogwu enrolled at Miami in 2013 and redshirted that season. He played in nine games as a redshirt freshman in 2014.
By his sophomore season in 2015, Odogwu was making inroads to become a starter. He made his first start in the season opener against Bethune-Cookman. Odogwu helped the offense gain 379 yards in a 45-0 blowout victory. He started again a week later as Miami ran for 226 yards and had 526 yards of total offense in a 45-20 win over Florida Atlantic.
Odogwu was a big part of Miami’s offense in 2016 before suffering a season-ending injury.