The Miami Dolphins (+4.5)
started the 2022 season with an AFC East rivalry game featuring the New England Patriots, followed by a non-divisional rivalry game against the Baltimore Ravens (-2.5). They came out of those two games with victories, setting themselves up with a 2-0 start that surprised most analysts. Now, however, they have their toughest test of the early season, heading into another AFC East rivalry game, this time as they host the Buffalo Bills (-4.5).
Buffalo comes into the weekend scoring 36 points per game through two weeks, the highest average in the NFL.