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March Madness 2025: Sweet 16 opening odds

The first weekend of March Madness has come and gone, narrowing every region down to four teams, each with serious Final Four aspirations.

FanDuel Sportsbook has evaluated the first two rounds of the NCAA Tournament and set its opening odds for the Sweet 16.

Here’s how Maryland men’s basketball fares against the remaining teams.

No. 4-seed Maryland men’s basketball (27-8, 14-6 Big Ten), West Region

Sweet 16 game odds: Maryland +6.5 vs. No. 1-seed Florida, O/U 156.5

National champion odds: +3800

West Region odds to make Final Four:

  • Florida -130
  • Texas Tech +260
  • Maryland +500
  • Arkansas +950

NCAA Tournament winner

  • Duke +220
  • Florida +430
  • Auburn +470
  • Houston +550
  • Alabama +1600
  • Texas Tech +1600
  • Tennessee +1600
  • Michigan State +2400
  • Arizona +4300
  • Kentucky +6500