For the first time in five years, Villanova will not open the Big East Tournament as the No. 1 seed.
The Wildcats finished 14-4 in the conference and finished with the second seed. Xavier earned the top seed following a 15-3 mark in conference play.
Villanova (27-4) received a double bye and will open the quarterfinal round against No. 7 seed Marquette on Thursday night at Madison Square Garden.
Marquette (19-12) finished 9-9 in the Big East during the regular season and squeaked past 10th-seeded DePaul 72-69 on Wednesday. Andrew Rowsey led the Golden Eagles with 25 points while Sam Hauser added 16.