The Reds will definitely be without Lisandro Martinez and Kobbie Mainoo after the pair picked up second-half bookings in Sunday's 4-0 victory over Everton.
By totting up five yellow cards in the division, they must serve a one-game suspension.
However, there is good news with the possible inclusion of Leny Yoro in a matchday squad for the first time since his summer move from Lille.
"We have one more training session to see it," Amorim said at a press conference at Old Trafford. "Maybe Leny Yoro is going to be in the squad.
"I felt he’s in a good moment now, his fitness is better, so I think he is going to be in the squad.