The famous red shirts will be adorned with an embroidered poppy, just as they were for the home game against Brighton & Hove Albion in November 2019 - as seen in our image of Dan James above.
As a further mark of respect for those who have lost their lives in conflicts across the world, a minute's silence will be held prior to kick-off at 16:30 GMT.
The silence will also honour United and England legend Nobby Stiles, who sadly passed away on Friday.
The Premier League’s support for the Poppy Appeal has resulted in more than £2.