The Reds are without suspended pair Lisandro Martinez and Marcel Sabitzer, plus injured players Christian Eriksen, Donny van de Beek, Scott McTominay, Antony and Anthony Martial.
It means the boss will have to tinker with his line-up to face impressive La Liga leaders Barcelona on their home patch, with kick-off at 17:45 GMT.
During an exclusive chat with MUTV's Liam Bradford, the two pundits, who are in the Catalan capital to cover the game live for BT Sport, forwarded their own views on the dilemmas Ten Hag will have been mulling over in the build-up to the Europa League play-off.