The quarter-final second leg at Old Trafford (20:00 BST) is all square at 2-2, following Rayan Cherki's equaliser with virtually the last kick of the game in France, after goals by Leny Yoro and Joshua Zirkzee had overturned Thiago Almada's free-kick opener.
With the need for a raucous atmosphere at the Theatre of Dreams to back Ruben Amorim's side, anticipation is already increasing for a competition that represents our last chance of winning a trophy despite the well-documented difficulties in the Premier League.
Not only would glory in Bilbao on 21 May mean silverware for the third successive season but also a coveted spot in next term's Champions League.