The game, which will determine the overall victors by pitting the northern champions (United) against the southern winners (Chelsea) kicks off at 19:00 BST, with our MUTV coverage beginning at 18:45 BST.
The Reds won the U18 Premier League Cup earlier this season, beating Manchester City 2-1 in the final, and are now looking to cap an impressive and fruitful campaign with the league and cup double.
The youngsters have experienced great growth in 2023/24, with many members of Adam Lawrence's squad also turning out for Travis Binnion's Under-21s too.
Our Under-18s won the northern league and, should we beat Chelsea, will qualify for the 2024/25 UEFA Youth League.