The Manchester United right-back came off the bench for Luke Shaw in the weekend win at Everton, after missing the victory against Luton Town due to illness.
His ability in one-versus-one duels could be useful in Wednesday's 17:45 GMT kick-off, as the Reds come up against Galatasaray and former winger Zaha, with qualification for the UEFA Champions League knockout stages on the line.
Wan-Bissaka was absent from the 3-2 home defeat to the Super Lig champions due to injury but should be an option in Istanbul.