Sophia Smith scored in the 64th minute and the United States got revenge for a loss to Mexico earlier this year with a 1-0 victory in the rematch on Saturday.
The friendly match at Red Bull Arena was the first of two tune-up games for the United States ahead of the 2024 Olympics. The Americans will play Costa Rica on Tuesday at Audi Field in Washington before departing for France.
Mexico beat the United States for just the second time ever at the Concacaf Women's Gold Cup in late February.