The Reds entered an Under-21 side in the competition for the first time last year and won the group, before being beaten 3-2 by Tranmere Rovers in the knock-out stages in December, when Tahith Chong scored both goals.
It proved a thoroughly enjoyable exercise for lead coach Neil Wood, the staff and players, as it provides an excellent test for the youngsters.
The 2020/21 draw was made on Talksport 2 in August, with the Reds the last Premier League club out of the hat, joining Group B.
As well as Salford who are, of course, strongly associated with members of the 'Class of '92', Wood's side will also be up against Morecambe and Rochdale.