The Reds won 4-1 on the club's last visit to Clayton Wood at this level in January 2019, when Mason Greenwood was among the scorers, but although Neil Ryan's side dominated the game again this time around, several first-half chances were either spurned, or denied by Stoke's agile goalkeeper Paul Cooper.
The hosts came more into the contest as an attacking force during the second period, and while United continued to have most of the possession, the Potters produced some threatening moments on the break.
In fact, Stoke could have twice taken the lead themselves; the Reds were grateful to goalkeeper Dermot Mee for at least one vital save, while right-back Iestyn Hughes demonstrated his determination with an excellent recovery tackle.