The Reds continued our marvellous form of late with Wednesday's 3-1 win over Crystal Palace, which boosted the push to gain a Champions League spot.
We last met the Saints in December, a match which produced a blistering first half as goals from Romelu Lukaku and Ander Herrera cancelled out strikes from Stuart Armstrong and Cédric Soares in a 2-2 draw.
United are unbeaten in the last six games against Southampton, including a memorable victory at Wembley a few years ago.
Here’s everything you need to know ahead of the match…
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