The quarter-final in Germany is being played over a single leg at Stadion Koln as part of a revised format, after the tournament was paused during lockdown.
United last reached this stage of the competition in our run to winning the Europa League in 2017, while Copenhagen are in the last eight of a major European tournament for the first time in their history.
Here’s everything you need to know ahead of our clash with the Danish club...
WHICH TV CHANNEL IS IT ON?
Monday’s game will be broadcast live in the UK, on BT Sport, with kick-off set for 20:00 BST.