However, the Argentinian defender is expected to make a full recovery in time to be ready for the start of next season.
Martinez sustained the injury in the 86th minute of Thursday night’s 2-2 draw with Sevilla in the quarter-final of the UEFA Europa League.
Lisandro’s defensive partner Raphael Varane was also substituted with an injury at half-time in the same game and is expected to be out for a few weeks.
While Lisandro’s first season at United has sadly come to a premature end, it will remain a memorable one for the centre-back having made 45 club appearances whilst establishing himself as a firm fan favourite and helping the team to win the Carabao Cup.