The home clash, our reward for beating Liverpool 3-2 in the last round, will kick off at 19:30 GMT and is being shown live in the UK on BBC One.
David Moyes's Hammers are in excellent form and have progressed by beating Stockport County (1-0) and Doncaster Rovers (4-0), without conceding a goal in the competition.
FA CUP FIFTH-ROUND FIXTURES Wednesday 10 February Thursday 11 February Back to Top
Tuesday 9 February
Burnley v Bournemouth (17:30 GMT)
UNITED v West Ham (19:30 GMT)
Swansea City v Manchester City (17:30 GMT)
Leicester City v Brighton (19:30 GMT)
Everton v Tottenham (20:15 GMT)
Wolves v Southampton (17:30 GMT)
Barnsley v Chelsea (20:00)Recommended: