Antonio Valencia is back as captain for his first start in the Reds XI since the European home match against Valencia at the beginning of October.
He replaces Matteo Darmian who played in the Palace stalemate. Also returning to the starting line up for the first time in two months is Phil Jones, who last started in the Carabao Cup game against Derby County at Old Trafford in September. Jones comes in for the injured Victor Lindelof, while Luke Shaw is back after suspension.
In midfield Marouane Fellaini, who came on as a sub in the 0-0 draw with Palace, starts alongside Nemanja Matic and Fred.