After a short spell on the sidelines, Marcus Rashford returns to the United starting XI. He replaces Cristiano Ronaldo from the side that beat Sheriff Tiraspol away in the Europa League last month.
And Rashford isn't the only Red returning to the matchday squad this afternoon, with Anthony Martial named on the bench for the first time since our 2-1 win over Liverpool in August.
Bruno Fernandes retains the captain's armband in the absence of Harry Maguire, with the latter ruled out having picked up an injury on international duty for England.
Our final summer arrival, Antony, keeps his place down the right after scoring on his Premier League debut against Arsenal.