The Dutch champions retained the title, having been victorious last year.
First-half goals from Nicolas Tagliafico and Steven Berghuis were followed by a Sebastian Haller penalty to give Ten Hag's side a three-goal lead at the break. Bryan Brobbey and Edson Alvarez added another two in the second half to confirm Ajax as champions.
Ten Hag's side have sealed the title with one game to go - an away trip to Vitesse on Sunday. The outcome of that fixture no longer has a bearing for either side, as the hosts sit sixth in the Eredivisie table.
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