The Dane has been absent for almost six weeks due to a knee injury, but is expected to be part of the matchday squad for the upcoming match at London Stadium on Saturday (12:30 GMT).
His recovery is a welcome boost for United's midfield, which has also been without the influential Casemiro since early November's Carabao Cup defeat to Newcastle United.
Mason Mount has endured injury issues since joining in the summer too, leaving Ten Hag with limited options for tough games like last Sunday's trip to Anfield, where 18-year-old Kobbie Mainoo and the on-loan Sofyan Amrabat fought manfully against a confident Liverpool team.