For the fourth time in the last five years, the Reds are returning to America, a pre-season destination that has long been popular with players and staff because of the training facilities, stadia, passionate fans and team-bonding opportunities.
Past visits to the US have produced some memorable moments, on and off the pitch. Here are 10 of our favourites...
Do you remember the first time?
United's first trip to the USA was an epic post-season affair in May 1950, when Matt Busby’s burgeoning side played 12 friendlies against mainly local teams over a six-week period, taking in cities such as Fall River, St.