The Reds are looking to avenge the home league reverse and Carabao Cup exit to Spurs earlier in the season, and have had time on the training ground this week to prepare for the challenge in the capital.
Altay Bayindir, Tom Heaton, Jonny Evans, Lisandro Martinez, Luke Shaw and Mason Mount missed the Emirates FA Cup fourth-round win over Leicester City last Friday due to injury.
One player is a doubt this weekend due to illness and there are a couple of "issues" the boss is having to contend with.
"It has been a good week," he said at the press conference to preview the Spurs game.