The 19:30 GMT kick-off at Old Trafford presents an opportunity for the Reds to get back to winning ways and build on the comeback at Everton last time out.
The boss hosted a press conference at Carrington on Tuesday afternoon and revealed he does not expect any of his injured players to return to the matchday squad.
When quizzed on the subject, he replied: "No, I think it’s the same. They are improving but nobody is recovering for this game."
Jonny Evans, Lisandro Martinez, Luke Shaw, Toby Collyer, Kobbie Mainoo, Mason Mount and Amad have all been absent of late.