Ole Gunnar Solskjaer's Reds led through Jesse Lingard's early strike but conceded twice against the much-improved hosts after the break, through Dmitri Shomko and Di'Shon Bernard's unfortunate own goal.
We take a look at some of the key topics coming out of the Group L tie...
JESSE OFF THE MARK
Captain Lingard's first goal of the season was an excellent one, smashing a firm drive past home skipper Nenad Eric's despairing left hand from the edge of the box in the 10th minute. The midfielder celebrated in front of the travelling Red Army and clearly enjoyed the moment.