Two goals from Ilkay Gundogan were enough to seal the win for City, despite Bruno Fernandes levelling it in the first half.
While the result is disappointing, there were some key details that stood out from a United point of view, after Erik ten Hag's side missed out on the chance to record a domestic-cup double for the first time in our history.
From tactical switches, to impact substitutes and our amazing fans, here are eight of the key talking points that stood out at Wembley...
Manchester City 2 Manchester United 1
A TACTICAL SWITCH
When Ten Hag named his line-up prior to kick-off, there was something of a positional rejig for the likes of Fernandes.