Victory for United would earn the Reds a crucial three points in the Premier League, and Solskjaer wants his team to be quick out of the blocks.
The Norwegian manager has a good record in games against City, winning more games against Blues boss Pep Guardiola than he's lost, a feat achieved by no other manager who's faced off against the Catalan on five or more occasions.
Last season's home derby at Old Trafford was hampered in its intensity by the lack of fans inside the ground. This season's will be very different.
"It's a special one of course," Solskjaer said of the game, when answering questions in his pre-match press conference on Friday afternoon.