Despite the fixture schedule wreaking havoc for the Reds this week, and prompting 10 changes to the line-up for the 2-1 defeat to Leicester City, any test against the Merseysiders is a perfect one in the mind of the manager.
Victory for his side would not only seal second spot in the Premier League but deliver a huge blow to the visitors' hopes of reaching next season's Champions League.
Speaking to MUTV's Stewart Gardner, he said he hoped any fatigue will not be a factor as the two giants meet in the rearranged fixture at Old Trafford tonight (20:15 BST kick-off).